Older people with dementia often depend on caregivers to manage their medications. The complexity of medication regimens in this population can impede medication adherence (i.e., taking medications as prescribed), which may compromise the effectiveness of treatment and increase the cost and burden of illness. Different technological devices have been used to improve medication adherence, however, these devices are often not evidence-based or designed with end-user involvement, thereby affecting their acceptability by people living with dementia and their caregivers. This in turn, can influence the effectiveness and uptake of such devices. This study aims to explore the challenges of medication adherence for both older people with dementia and their caregivers to guide the development of future technological solutions that can be effective, practical and sustainable.