Limited studies have examined the relationship between quality of life and lifestyle behaviors. The purpose of this study is to examine the perceptions of quality of life among young Iranian women and its association with lifestyle behaviors.This cross-sectional study was conducted among 391 young women selected through a cluster convenience sampling strategy in Shiraz, Iran. WHOQoL-BREF and satisfaction with life scales were used to measure subjective well-being. The International Health and Behavior survey was used for measuring lifestyle behaviors.Young Iranian women were averagely dissatisfied with their life circumstances. The score of psychological quality of life, and social quality of life were below average. According to the findings, higher quality of life is positively related to healthier lifestyle behaviors. Multiple regression analysis showed that smoking and physical activity are the main predictors of quality of life. Findings also demonstrate that diminished quality of life was significantly associated with older age, low income, being single, low level of religiosity, smoking and low levels of physical activity.In order to improve the situation of young Iranian women, the findings that should be sources of concern to policy makers include the average dissatisfaction with circumstances of life particularly in terms of psychological, social and environmental quality of life. While the health system focus is often upon addressing unhealthy lifestyle behaviors, policy initiatives aimed at improving these circumstances of life for young Iranian women would be of substantial medium to long-term benefit to their wellbeing.