A Parallel Machine Learning Framework for Detecting Alzheimer’s Disease

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Knox, SA
Chen, T
Su, P
Antoniou, G
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2021
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Padoa, Italy

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Abstract

This paper proposes a parallel machine learning framework for detecting Alzheimer’s disease through T1-weighted MRI scans localised to the hippocampus, segmented between the left and right hippocampi. Feature extraction is first performed by 2 separately trained, unsupervised learning based AutoEncoders, where the left and right hippocampi are fed into their respective AutoEncoder. Classification is then performed by a pair of classifiers on the encoded data from the AutoEncoders, to which each pair of the classifiers are aggregated together using a soft voting ensemble process. The best averaged aggregated model results recorded was with the Gaussian Naïve Bayes classifier where sensitivity/specificity achieved were 80%/81% respectively and a balanced accuracy score of 80%.

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Lecture Notes in Computer Science

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12960

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Biomedical engineering

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Knox, SA; Chen, T; Su, P; Antoniou, G, A Parallel Machine Learning Framework for Detecting Alzheimer’s Disease, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2021, 12960, pp. 423-432