Prediction of cutting force has great significance for controlling the micro-end-milling processes. In this study, a mechanics model for exactly prediction cutting force is comprehensively established by considering the variety of entry and exit angles for each engaged cutting edge and an accurate instantaneous uncut chip thickness (IUCT). The determination of IUCT has considered the combination of the minimum chip thickness, tool run-out, and the material's elastic recovery, which is embedded in the cutting force model. Further, cutting force coefficients as function of uncut chip thickness have been calculated by using finite element method (FEM). To verify the reliability of the presented cutting force model, a series of experiments for cutting force are conducted and experimental results are compared to cutting force predicted. The results demonstrate that the cutting force predicted is well in agreement with that of measured. The effects of elastic recovery and tool run-out on cutting force also are investigated. Some conclusion can be drawn that elastic recovery can more obviously affect the cutting force predicted with smaller the feed per tooth, the errors of experimental and predicted is getting smaller with increasing the cutting depth, the slight change of tool run-out will lead to a great variation in cutting force.