Liquid marble is a promising microreactor platform that recently attracts significant research interest owing to their ability to accommodate a wide range of micro reactions. However, the use of destructive and ex-situ methods to monitor reactions impairs the potential of liquid-marble-based microreactors. This paper proposes a non-destructive, in situ, and cost-effective digital-imaging-based colourimetric monitoring method for transparent liquid marbles, with the example of the enzymatic hydrolysis of starch. The colourimetric reaction between starch and iodine produces a complex that exhibits a dark blue colour. We found that the absorbance of red channel of digital images showed a linear relationship with starch concentration with high sensitivity and repeatability. This digital-imaging based-colourimetric method was used to study the hydrolysis of starch by α-amylase. The results showed high accuracy and applicability of first-order kinetic for this reaction. The demonstration of digital-imaging-based colourimetry indicates the potential of liquid marble-based microreactors.