We commend Yuan et al. for having discussed the PRISMA approach ostentatiously. In accordance with the PRISMA guidelines, Yuan et al. have performed a thorough systematic review and meta-analysis examining the diagnostic performance of mammography alone plus Ultrasound (US) for breast cancer in women with dense breasts, as well as that of follow-up US in women with dense breasts and negative mammography results. We also commend the authors who have comprehensively collated data regarding recall rate, biopsy rate and biopsy-referenced positive predictive value (PPV) across multiple other studies.1 There are several critical points that may need to be elucidated so as to augment the validity of the authors’ multifactorial findings.