Synthesis of N-alkylsulfonamides by borane-dimethyl sulfide reduction of N-acylsulfonamides

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James, Samantha N
Coster, Mark J
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2015
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Abstract

A convenient synthesis of N-alkylsulfonamides in good to excellent yields by reduction of N-acylsulfonamides using BH3瓍e2 is described. This methodology presents an attractive alternative for sulfonamide formation.

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Tetrahedron Letters

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56

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© 2015, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.

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Medicinal and biomolecular chemistry

Organic chemistry

Organic chemical synthesis

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