State-Wide Utilization and Performance of Traditional and Cell-Free DNA-Based Prenatal Testing Pathways: The Victorian Perinatal Record Linkage (PeRL) Study
File version
Accepted Manuscript (AM)
Author(s)
Hui, L
Poulton, A
Kluckow, E
Hutchinson, B
Pertile, MD
Bonacquisto, L
Gugasyan, L
Kulkarni, A
Harraway, J
Howden, A
McCoy, R
Da Silva Costa, F
Menezes, M
et al.
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
Size
File type(s)
Location
License
Abstract
In recent years, the use of combined first-trimester screening (CFTS) and cell-free DNA (cfDNA) screening has increased. With the rise of CFTS and cfDNA prenatal testing, there has been a dramatic decrease in the number of invasive diagnostic tests performed during pregnancy. In this study, the authors performed a record-linkage study to obtain state-wide cfDNA, CFTS, and postnatal cytogenetic data to determine the utilization and performance of different genetic screening pathways, as well as to determine the number of major chromosomal abnormalities detected following a low-risk CFTS or cfDNA result in Australia.
Journal Title
Obstetrical and Gynecological Survey
Conference Title
Book Title
Edition
Volume
76
Issue
1
Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
© 2021 LWW. This is a non-final version of an article published in final form in Obstetrical and Gynecological Survey, 2021, 76 (1), pp. 3-5. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal link for access to the definitive, published version.
Item Access Status
Note
Access the data
Related item(s)
Subject
Paediatrics
Persistent link to this record
Citation
Lindquist, A; Hui, L; Poulton, A; Kluckow, E; Hutchinson, B; Pertile, MD; Bonacquisto, L; Gugasyan, L; Kulkarni, A; Harraway, J; Howden, A; McCoy, R; Da Silva Costa, F; Menezes, M; et al., State-Wide Utilization and Performance of Traditional and Cell-Free DNA-Based Prenatal Testing Pathways: The Victorian Perinatal Record Linkage (PeRL) Study, Obstetrical and Gynecological Survey, 2021, 76 (1), pp. 3-5