Uterine Artery Doppler in Screening for Preeclampsia and Fetal Growth Restriction

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Pedroso, Marianna Amaral
Palmer, Kirsten Rebecca
Hodges, Ryan James
Costa, Fabricio da Silva
Rolnik, Daniel Lorber
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2018
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Abstract

Objective To perform a comprehensive review of the current evidence on the role of uterine artery Doppler, isolated or in combination with other markers, in screening for preeclampsia (PE) and fetal growth restriction (FGR) in the general population. The review included recently published large cohort studies and randomized trials. Methods A search of the literature was conducted usingMedline, PubMed, MeSH and ScienceDirect. Combinations of the search terms “preeclampsia,” “screening,” “prediction,” “Doppler,” “Doppler velocimetry,” “fetal growth restriction,” “small for gestational age” and “uterine artery” were used. Articles in English (excluding reviews) reporting the use of uterine artery Doppler in screening for PE and FGR were included. Results Thirty articles were included. As a single predictor, uterine artery Doppler detects less than 50% of the cases of PE and no more than 40% of the pregnancies affected by FGR. Logistic regression-based models that allow calculation of individual risk based on the combination of multiple markers, in turn, is able to detect _ 75% of the cases of preterm PE and 55% of the pregnancies resulting in small for gestational age infants. Conclusion The use of uterine artery Doppler as a single predictive test for PE and FGR has poor accuracy. However, its combined use in predictive models is promising, being more accurate in detecting preterm PE than FGR.

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Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics

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40

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5

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© 2018 by Thieme Revinter Publicações Ltda, Rio de Janeiro, Brazil. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International (CC BY-NC-ND 4.0) License, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.

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Radiology and organ imaging

Obstetrics and gynaecology

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Life Sciences & Biomedicine

screening

preeclampsia

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Pedroso, MA; Palmer, KR; Hodges, RJ; Costa, FDS; Rolnik, DL, Uterine Artery Doppler in Screening for Preeclampsia and Fetal Growth Restriction, Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, 2018, 40 (5), pp. 287-293

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