The election of Donald Trump as president of the United States in 2016 may have seemed quite unlikely had it not been for a number of time-period factors on which he and his campaign team successfully capitalized. One major factor was the dramatic rise, since 9/11, in anti-Islam and anti-Muslim sentiments among a significant proportion of Americans, which Trump strategically conflated with broader concerns about immigration and national security. During his time in office, Trump has consistently exploited such sentiments, alienating U.S. Muslim communities but maintaining close relations with certain Muslim regimes internationally, namely Saudi Arabia, while fomenting tensions with others, particularly the Islamic Republic of Iran. Trump has engaged in a particular style of politics that has been referred to as 'Trumpism'. This chapter explores the meaning of Trumpism in the context of Trump's rhetoric and relations with domestic Muslim communities and selected Muslim-majority countries. Part 1 of this chapter discusses domestic issues beginning with Trump's Islamophobic rhetoric during the 2016 election campaign, rhetoric on terrorism, the Muslim travel ban, and relations with U.S. Muslims, including attacks on two Democratic (and Muslim) congresswomen (Ilhan Omar and Rashida Tlaib). Part 2 addresses international issues including Trump's policies regarding the Israel-Palestine conflict, withdrawal from the Joint Comprehensive Plan of Action (Iran Nuclear Deal) and conflict with Iran, and ongoing support for Saudi Arabia amidst its war in Yemen and the murder of The Washington Post journalist Jamal Khashoggi. This chapter will attempt to identify some potential medium to long-term impacts of Trumpism on Islam-West relations.