DNA Methylation in Adipose Tissue and Metabolic Syndrome (Editorial)
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Brown, Lindsay
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Abstract
Epigenetics is the study of heritable phenotype changes that do not involve alterations in the DNA sequence with the processes including DNA methylation, histone modifications and RNA-associated silencing [1,2]. Castellano-Castillo and colleagues have analysed the impact of metabolic syndrome on the global DNA methylation pattern and the DNA methylation of several genes in visceral adipose tissue [3]. They concluded that DNA methylation in adipose tissue of these patients is related to the aetiology of the syndrome. The role of DNA methylation in genes for adipogenesis, inflammation and lipid metabolism provides logical explanations for these changes in the development and progression of metabolic syndrome [3].
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Journal of Clinical Medicine
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9
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9
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© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Epigenetics (incl. genome methylation and epigenomics)
Medical biochemistry and metabolomics
Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
DNA methylation
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Panchal, SK; Brown, L, DNA Methylation in Adipose Tissue and Metabolic Syndrome (Editorial), Journal of Clinical Medicine, 2020, 9 (9), pp. 2699