The use of negative pressure wound therapy (vacuum dressings) is increasing in surgical incisions where there is a high risk of dehiscence, seroma, and other wound healing complications. In response to the growing use of various vacuum dressings in the prophylactic treatment of surgical incisions, a product evaluation of three products was undertaken in a hospital in Queensland, Australia. In this evaluation, the three aspects of product usability were considered in a specified context of use: 1) effectiveness; 2) efficiency; and 3) satisfaction. The perspectives of the treating medical officers, nursing staff and patients were elicited. Prior to the commencement, a two-week product-specific education program was implemented. Fifteen patients were recruited, with five patients for each dressing product. The evaluation was completed in its entirety for 13/15 (86.6%) of the dressing products. The majority of surgeons and ward nurses, who used the negative pressure dressing products, recommended them. Overall, surgeons preferred the Prevena頷hile nurses and patients preferenced the PICO頰roduct. The products evaluated here have individual features that make them appropriate to be used for certain incisional wounds. Product selection should be based on the type of surgery, the amount of wound ooze anticipated, and the level of risk associated with the incision. However, in the current economic climate, product cost will ultimately dictate product use.