Opto-acousto-fluidic microscopy for three-dimensional label-free detection of droplets and cells in microchannels
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Jin, Tian
Yan, Ruopeng
Qi, Weizhi
Huang, Tianye
Ding, Huafeng
Tan, Say Hwa
Nam-Trung, Nguyen
Xi, Lei
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Abstract
This paper reports a novel method, opto-acousto-fluidic microscopy, for label-free detection of droplets and cells in microfluidic networks. Leveraging the optoacoustic effect, the microscopic system possesses capabilities of visualizing flowing droplets, analyzing droplet contents, and detecting cell populations encapsulated in droplets via the sensing of acoustic waves induced by the intrinsic light-absorbance of matter.
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Lab on a Chip
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18
Issue
9
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© 2018 Royal Society of Chemistry. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal website for access to the definitive, published version.
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Chemical sciences
Other chemical sciences not elsewhere classified
Engineering