Systematic review methodology can be distinguished from narrative reviews of the literature through its emphasis on transparent, structured and comprehensive approaches to searching the literature and its requirement for formal synthesis of research findings. There appears to be relatively little use of the systematic review methodology within the higher education sector. This paper outlines the systematic review methodology, including variations, explores debates regarding systematic reviews from the educational literature and describes particular issues for its application within higher education. We conclude that thoughtful use of the systematic review methodology may be of benefit to the sector.