Periodontitis and oral cancer - current concepts of the etiopathogenesis
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Barati, I
Badiei, M
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Abstract
Gingival tissues are attacked by oral pathogens which can induce inflammatory reactions. The immune-inflammatory responses play essential roles in the patient susceptibility to periodontal diseases. There is a wealth of evidence indicating a link between chronic inflammation and risk of malignant transformation of the affected oral epithelium. Periodontitis is associated with an increased risk of developing chronic systemic conditions including autoimmune diseases and different types of cancers. Besides, some risk factors such as smoking , alcohol consumption and human papilloma virus have been found to be associated with both periodontitis and oral cancer. This review article aimed to study the current concepts in pathogenesis of chronic periodontitis and oral cancer by reviewing the related articles.
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Oncology Reviews
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14
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1
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© The Author(s) 2021. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
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Dentistry
Oncology and carcinogenesis
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Irani, S; Barati, I; Badiei, M, Periodontitis and oral cancer - current concepts of the etiopathogenesis, Oncology Reviews, 2020, 14 (1), pp. 23-34