Machine learning is a powerful tool for data classification and has been used to classify movement data recorded by wearable inertial sensors in general living and sports. Inertial sensors can provide valuable biofeedback in combat sports such as boxing; however, the use of such technology has not had a global uptake. If simple inertial sensor configurations can be used to automatically classify strike type, then cumbersome tasks such as video labelling can be bypassed and the foundation for automated workload monitoring of combat sport athletes is set. This investigation evaluates the classification performance of six different supervised machine learning models (tuned and untuned) when using two simple inertial sensor configurations (configuration 1—inertial sensor worn on both wrists; configuration 2—inertial sensor worn on both wrists and third thoracic vertebrae [T3]). When trained on one athlete, strike prediction accuracy was good using both configurations (sensor configuration 1 mean overall accuracy: 0.90 ± 0.12; sensor configuration 2 mean overall accuracy: 0.87 ± 0.09). There was no significant statistical difference in prediction accuracy between both configurations and tuned and untuned models (p > 0.05). Moreover, there was no significant statistical difference in computational training time for tuned and untuned models (p > 0.05). For sensor configuration 1, a support vector machine (SVM) model with a Gaussian rbf kernel performed the best (accuracy = 0.96), for sensor configuration 2, a multi-layered perceptron neural network (MLP-NN) model performed the best (accuracy = 0.98). Wearable inertial sensors can be used to accurately classify strike-type in boxing pad work, this means that cumbersome tasks such as video and notational analysis can be bypassed. Additionally, automated workload and performance monitoring of athletes throughout training camp is possible. Future investigations will evaluate the performance of this algorithm on a greater sample size and test the influence of impact window-size on prediction accuracy. Additionally, supervised machine learning models should be trained on data collected during sparring to see if high accuracy holds in a competition setting. This can help move closer towards automatic scoring in boxing. View Full-Text