In recent years, hydrogen has constituted a clean energy carrier that can be gained by the use of renewable electricity. The most preliminary stage in the process of renewable hydrogen generation is to find the best place for exploiting the most energy. Thus, this study seeks to optimize the process of location selection for the construction of a solar power station. This evaluation is performed on 12 cities of Isfahan in Iran. After ascertaining 11 criteria of key importance, Window Data Envelopment Analysis (WDEA) Method is used to prioritize the cities according to the data for a period of 11 years. Consequently, the most promising site is technically and economically scrutinized as to hydrogen production using solar electricity. Results pertaining to the first part of the study showed that the city of Natanz was efficient over the entire studied period. Considering 4 cases of different performance rates, annual electricity generation using solar panel model X21-345 and hydrogen production using an alkaline electrolyzer were estimated for the city. The estimations indicated that hydrogen production under the worst and the best cases would be 2.22 kg and 5.55 leading to energy efficiency of between 2.5% and 7.1%, respectively. Finally, economic assessment proved promising results in which Levelized Cost of Electricity (LCOE) would be between 0.5317 and 1.6272 $/kWh and Levelized Cost of Hydrogen (LCOH) would vary from 0.7911 to 1.6778 $/kg.