Dihydro-resveratrol—A potent dietary polyphenol
No Thumbnail Available
File version
Author(s)
A. Gakh, Andrei
Anisimova, Natalia
V. Kiselevsky, Mikhail
V. Sadovnikov, Sergey
N. Stankov, Ivan
V. Yudin, Mikhail
A. Rufanov, Konstantin
Krasavin, Mikhail
V. Sosnov, Andrey
Anisimova, Natalia
V. Kiselevsky, Mikhail
V. Sadovnikov, Sergey
N. Stankov, Ivan
V. Yudin, Mikhail
A. Rufanov, Konstantin
Krasavin, Mikhail
V. Sosnov, Andrey
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
2010
Size
File type(s)
Location
License
Abstract
Dihydro-resveratrol (dihydro-R), a prominent polyphenol component of red wine, has a profound proliferative effect on hormone-sensitive tumor cell lines such as breast cancer cell line MCF7. We found a significant increase in MCF7 tumor cells growth rates in the presence of picomolar concentrations of this compound. The proliferative effect of dihydro-R was not observed in cell lines that do not express hormone receptors (MDA-MB-231, BT-474, and ?-562).
Journal Title
Bioorganic & Medicinal Chemistry Letters
Conference Title
Book Title
Edition
Volume
20
Issue
20
Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status
Note
Access the data
Related item(s)
Subject
Biologically Active Molecules
Medicinal and Biomolecular Chemistry
Organic Chemistry
Pharmacology and Pharmaceutical Sciences