The laser-induced fluorescence can be used to detect and diagnose dental caries, calculus and bacterial 7 biofilms in dental applications. As such the molecular fluorescence phenomenon has been illustrated 8 scientifically and the literatures relating the fluorescence properties of dental tissues have been explored till the 9 literature reviews ultimately led up to the development of the current Laser Fluorescence (LF) devices. These 10 LF devices have been introduced clinically for dental caries, calculus and bacterial detection to replace 11 inaccurate contemporary detection tools. The future for LF technologies in diagnostic dentistry has been 12 indicated as accurate and potentially applicable in a wide range in restorative dentistry, periodontology and 13 endodontics.