Kingamide A, a new indole alkaloid from the ascidian Leptoclinides kingi

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Liberio, Michelle S
Sooraj, Dhanya
Williams, Elizabeth D
Feng, Yunjiang
Davis, Rohan A
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2011
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Abstract

Chemical investigation of the CH2Cl2/MeOH extract from the Australian ascidian Leptoclinides kingi led to the isolation of a new brominated indole alkaloid, kingamide A (1). The planar structure of kingamide A was elucidated following the interpretation of 1D/2D NMR and MS data, and the absolute configuration was determined using Marfey’s method. This is the first report of a natural product from L. kingi.

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Tetrahedron Letters

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52

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50

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Medicinal and biomolecular chemistry

Organic chemistry

Organic chemistry not elsewhere classified

Biochemistry and cell biology

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