Pearls & Oy-sters: Hemorrhagic Myelitis Following SARS-CoV-2 Infection

No Thumbnail Available
File version
Author(s)
Toljan, K
Mahadeen, A
Amin, M
Rensel, M
Jones, SE
Ontaneda, D
Kunchok, AC
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
2023
Size
File type(s)
Location
License
Abstract

Hemorrhage in the setting of myelitis is rarely seen in clinical practice. We report a series of 3 women aged 26, 43, and 44 years, who presented with acute hemorrhagic myelitis within 4 weeks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Two required intensive care, and 1 had severe disease with multiorgan failure. Serial MRI of the spine demonstrated T2-weighted hyperintensity with T1-weighted postcontrast enhancement in the medulla and cervical spine (patient 1) and thoracic spine (patients 2 and 3). Hemorrhage was identified on precontrast T1-weighted, susceptibility-weighted, and gradient echo sequences. Distinct from typical inflammatory or demyelinating myelitis, clinical recovery was poor in all cases, with residual quadriplegia or paraplegia, despite immunosuppression. These cases highlight that although hemorrhagic myelitis is rare, it can occur as a post/parainfectious complication of SARS-CoV-2 infection.

Journal Title

Neurology

Conference Title
Book Title
Edition
Volume

101

Issue

6

Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status
Note
Access the data
Related item(s)
Subject

Clinical sciences

Neurosciences

Persistent link to this record
Citation

Toljan, K; Mahadeen, A; Amin, M; Rensel, M; Jones, SE; Ontaneda, D; Kunchok, AC, Pearls & Oy-sters: Hemorrhagic Myelitis Following SARS-CoV-2 Infection, Neurology, 2023, 101 (6), pp. E672-E676

Collections