This descriptive research aimed to study happiness of nursing students at the Faculty of Nursing, Khon Kaen University. The population included 636 nursing students in years 1- 4. The instruments included the demographic data, Thai Mental Health Indicator, coping methods, and ways to increase happiness. Descriptive statistics, chi-square, one way ANOVA and t-test were used to analyze the data. The study found significant differences in happiness scores among the four years. The first year students showed the highest mean happiness score, followed by fourth year, second and third year, respectively. The first three coping methods used included accepting self, positive thinking and seeking consultation from friends.