Rigidin E, a new pyrrolopyrimidine alkaloid from a Papua New Guinea tunicate Eudistoma species.
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V. Christensen, Lane
D. Richardson, Adam
da Rocha, Rosana Moreira
M. Ireland, Chris
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Abstract
A new pyrrolo[2,3-d]pyrimidine alkaloid, rigidin E (I), and the known metabolites rigidin (II) and 1-methylherbipoline (III) were isolated from a Papua New Guinea tunicate Eudistoma sp. A combination of spectroscopic data were used to det. the structures of these metabolites. Alkaloids I, II and III showed only minimal cell growth inhibition when assayed for cytotoxicity against HCT 166 and A431 cancer cell lines.
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Marine Drugs
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1
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© 2003 MDPI (http://www.mdpi.org). The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
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Physical chemistry
Pharmacology and pharmaceutical sciences