Aim: To determine the shaping and centering ability of Twisted File (TF), HERO Shaper file and the ProFile .06 in simulated curved root canals. Methodology: Sixty simulated root canals of either 20o, 10 mm radius (n = 30) or 30o, 6 mm radius (n = 30) canal curvatures were prepared with three file systems in a variable tip, modified Crown Down technique. Mean changes on the inner and outer canal walls were analysed for shaping and centering ability of the systems and analysed using ANOVA. Result: There were no significant differences in canal preparations between the 20 and 30 canal curvatures with each system (p > 0.05). All file systems produced well-tapered canal preparations. Overall HERO shaper removed the least canal wall material (p< 0.05), while the other two systems were comparable (p> 0.05). TF showed a better ability to remove inner canal wall material and remain centered in the apical third (p< 0.05), while Profile and HERO transported to the outer wall. Conclusion: All systems produced clinically acceptable canal shapes. TF files showed a better ability to instrument the inner canal wall and remain centered in the apical region. HERO Shaper file was observed to remove the least material in all regions.