Caregiver broader autism phenotype does not moderate the effect of early caregiver-mediated support on infant language outcomes

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O'Connor, Erin
Treyvaud, Karli
Green, Cherie C
Green, Jonathan
Iacono, Teresa
Maybery, Murray
Segal, Leonie
Slonims, Vicky
Varcin, Kandice J
Wan, Ming Wai
Whitehouse, Andrew
Hudry, Kristelle
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2025
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Abstract

Caregiver-mediated supports in general have shown mixed evidence for enhancing language outcomes in infants at higher likelihood of autism. While caregivers play a substantial role in caregiver-mediated supports, little is known about whether caregivers’ own subclinical autistic features – known as broader autism phenotype (BAP) – may moderate infant language outcomes. In secondary analysis of trial data, we examined whether caregiver BAP moderated the effectiveness of the iBASIS caregiver-mediated support program (received when infants were mean aged 12–18 months) for infant language outcomes (measured on parent-reported and direct assessment of receptive and expressive language). While lower caregiver BAP was linked to increased parent-reported infant vocabulary growth in general terms, it did not actually moderate the effect of the caregiver-mediated support program on those infant language outcomes. In relative terms therefore, infants of caregivers with both higher and lower BAP benefited equally from this support on parent-report compared to the comparison group. Caregiver BAP is associated with slower vocabulary growth in infants, but caregivers with autistic features can be recommended for this caregiver-mediated video-feedback based program, as their infants benefitted from such support.

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Infant Behavior and Development

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80

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© 2025 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Biomedical and clinical sciences

Psychology

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O'Connor, E; Treyvaud, K; Green, CC; Green, J; Iacono, T; Maybery, M; Segal, L; Slonims, V; Varcin, KJ; Wan, MW; Whitehouse, A; Hudry, K, Caregiver broader autism phenotype does not moderate the effect of early caregiver-mediated support on infant language outcomes, Infant Behavior and Development, 2025, 80, pp. 102093

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