The gap between the aorta and the superior vena cava: A sonographic sign of persistent left superior vena cava and associated abnormalities
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Rolnik, Daniel L
Ramkrishna, Jayshree
Costa, Fabricio da Silva
Meagher, Simon
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Abstract
Objectives: To assess the distance between the right superior vena cava (SVC) and the aorta in fetuses with bilateral superior vena cava as a possible sonographic marker for this. Methods: This was a nested case-control study including 20 cases of bilateral SVC and 40 gestational age-matched controls. The distance between the right SVC and the aorta was measured at the level of the three-vessel trachea view in stored images, as well as the diameters of the aorta and the right SVC. Results: The distance between the aorta and the right SVC was significantly larger in the cases of a left SVC compared with controls, P <.001. A distance of 2.0 mm or more was found in 70% of the cases and 5% of the controls, with a gestational-age adjusted area under the receiver-operating characteristics (ROC) curve for the diagnosis of left SVC of 0.93 (95% CI 0.87-0.99). The aorta and the right SVC were significantly smaller in cases compared with controls, and there was a significant association with other cardiac and extracardiac abnormalities amongst cases of persistent left SVC. Conclusion: An increased distance between the aorta and the right SVC is associated with the diagnosis of bilateral SVC.
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Prenatal Diagnosis
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39
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13
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© 2019 John Wiley & Sons, Ltd. This is the peer reviewed version of the following article: The gap between the aorta and the superior vena cava: A sonographic sign of persistent left superior vena cava and associated abnormalities, Prenatal Diagnosis, 2019, 39 (13), pp. 1213-1219, which has been published in final form at https://doi.org/10.1002/pd.5569. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
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Clinical sciences
Science & Technology
Life Sciences & Biomedicine
Genetics & Heredity
Obstetrics & Gynecology
LEFT BRACHIOCEPHALIC VEIN
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Wertaschnigg, D; Rolnik, DL; Ramkrishna, J; Costa, FDS; Meagher, S, The gap between the aorta and the superior vena cava: A sonographic sign of persistent left superior vena cava and associated abnormalities, Prenatal Diagnosis, 2019, 39 (13), pp. 1213-1219