jats:titleABSTRACT</jats:title>jats:pPsychosocial factors are well‐known determinants of workers' health and well‐being, and considerable research exists on how organisations can manage stress at work. Most existing research draws on theories from psychological sciences and applies them using a narrow approach, and consequently, recommendations usually involve organisations minimising demands on employees and maximising organisational resources. Despite these advances, research continues to find differences between the well‐being of workers operating under similar working conditions, suggesting a broader understanding of the mechanism through which psychosocial hazards impact well‐being is needed. Based on survey data from over 800 employees in Malaysia, we find that deterioration in worker well‐being resulting from psychosocial hazards at work is moderated by how safe employees feel to speak up about interpersonal problems at work (known as psychological safety). We conclude that a broader HR approach that looks beyond individual factors in work demands and resources is needed to manage stress at work.</jats:p>