Orthotopic Xenograft Mouse Model in Esophageal Squamous Cell Carcinoma
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Ip, JCY
Ko, JMY
Tao, L
Lam, AK
Lung, ML
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Abstract
Orthotopic xenograft model recapitulates the faithful organ-specific microenvironment and facilitates analyses involving tumor-stromal interactions that are crucial for developing new-generation cancer therapy. Herein, we describe the detailed rationales and protocols of a versatile orthotopic xenograft model for esophageal squamous cell carcinoma.
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Esophageal Squamous Cell Carcinoma: Methods and Protocols
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2129
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Other chemical sciences
Biochemistry and cell biology
Bioluminescence imaging
Esophageal squamous cell carcinoma
Live animal imaging
Orthotopic model
Xenograft
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Citation
Yu, VZ; Ip, JCY; Ko, JMY; Tao, L; Lam, AK; Lung, ML, Orthotopic Xenograft Mouse Model in Esophageal Squamous Cell Carcinoma, Esophageal Squamous Cell Carcinoma: Methods and Protocols, 2020, 2129, pp. 149-160