In vitro bioassays to assess drinking water quality
File version
Accepted Manuscript (AM)
Author(s)
Escher, BI
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
Size
File type(s)
Location
Abstract
In vitro assays indicative of different stages of cellular toxicity pathways have been applied to both source water and drinking water. The majority of studies showed a decrease in receptor-mediated effects after drinking water treatment due to the removal of micropollutants, while reactive toxicity typically increased after chlorination due to the formation of disinfection by-products. Using both chemical analysis and bioanalysis, iceberg modelling can be applied to determine which chemicals are contributing to the observed effect, though one limitation is that typical sample pretreatment for bioanalysis fails to capture volatile chemicals. Bioassays are increasingly sensitive and effects can be detected in clean samples, thus effect-based trigger values can be applied to determine whether an effect in drinking water is acceptable.
Journal Title
Current Opinion in Environmental Science & Health
Conference Title
Book Title
Edition
Volume
Issue
Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
© 2018 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
Item Access Status
Note
This publication has been entered into Griffith Research Online as an Advanced Online Version.
Access the data
Related item(s)
Subject
Other environmental sciences not elsewhere classified