Mathematical Models for Topical and Transdermal Drug Products
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Author(s)
Anissimov, Yuri
Roberts, Michael S.
Roberts, Michael S.
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Shah V.P., Maibach H.I. and Jenner J.
Date
2014
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Abstract
Mathematical models of epidermal and dermal transport, which includes transport of a solute through vehicle and various layers of the skin, metabolism in the skin and its subsequent distribution and clearance into systemic circulation from underlying tissues, play an essential role in development of topical and transdermal drug products and are reviewed in this chapter.
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Topical Drug Bioavailability, Bioequivalence, and Penetration
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2nd
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Mathematical Sciences not elsewhere classified