Solution-Phase Combinatorial Synthesis and Evaluation of Piperazine-2,5-dione Derivatives

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Loughlin, WA
Marshall, RL
Carreiro, A
Elson, KE
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2000
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Abstract

An efficient one-pot synthesis of a 61-membered combinatorial chemistry library of piperazine-2,5-diones was accomplished. Results of combinatorial synthesis, purification, analysis, and biological evaluation are described.

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Bioorganic & Medicinal Chemistry Letters

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10

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2

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Medicinal and biomolecular chemistry

Organic chemistry

Pharmacology and pharmaceutical sciences

History, heritage and archaeology

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