B-Raf mutation: A key player in molecular biology of cancer

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Rahman, MA
Salajegheh, A
Smith, RA
Lam, AK-Y
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2013
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Abstract

B-Raf is one of the more commonly mutated proto-oncogenes implicated in the development of cancers. In this review, we consider the mechanisms and clinical impacts of B-Raf mutations in cancer and discuss the implications for the patient in melanoma, thyroid cancer and colorectal cancer, where B-Raf mutations are particularly common.

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Experimental and Molecular Pathology

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95

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3

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Clinical sciences

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