Fathers are increasingly expected to engage in infant care. The early postpartum period has been described as a time when work-family conflict, lack of sleep, and fatigue are prominent themes. Research has demonstrated that these themes can have a deleterious effect on work safety. Lack of sleep and fatigue have been linked to workplace accidents, yet few studies have specifically investigated work-family conflict, sleep, and fatigue among men with infants. The need exists to specifically study and measure work-family conflict, sleep deprivation, and fatigue in relation to early fatherhood. Such research could have a direct effect on occupational health nursing practice.