Bromotyrosine Alkaloids from the Australian Marine Sponge Pseudoceratina verrucosa
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Pham, Ngoc B
Fechner, Gregory
Hooper, John NA
Quinn, Ronald J
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Abstract
Two new bromotyrosine alkaloids, pseudoceralidinone A (1) and aplysamine 7 (2), along with three known compounds were isolated from the Australian sponge Pseudoceratina verrucosa. Their structures were characterized by NMR and MS data and the synthetic route. Their cytotoxicity was evaluated against cancer cell lines (HeLa and PC3) and a noncancer cell line (NFF).
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Journal of Natural Products
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76
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4
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Chemical sciences
Medicinal and biomolecular chemistry not elsewhere classified
Biological sciences
Biomedical and clinical sciences