Relative quantitation of multi-antennary N-glycan classes: Combining PGC-LC-ESI-MS with exoglycosidase digestion
No Thumbnail Available
File version
Author(s)
Abrahams, Jodie L.
Packer, Nicolle H.
Campbell, Matthew P.
Packer, Nicolle H.
Campbell, Matthew P.
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
2015
Size
File type(s)
Location
License
Abstract
In the search for N-glycan disease biomarkers current glycoanalytical methods may not be revealing a complete picture of precious samples, and we may be missing valuable structural information that fall outside analysis windows. We report a targeted strategy combining PGC-LC-ESI-MS with exoglycosidases to improve the relative quantitation of tri and tetra-antennary glycan classes.
Journal Title
Analyst
Conference Title
Book Title
Edition
Volume
140
Issue
16
Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status
Note
Access the data
Related item(s)
Subject
Analytical chemistry
Analytical chemistry not elsewhere classified
Other chemical sciences