In many countries, there are no professional standards determining attributes, praxis, effectiveness and evaluation for teachers of relationships and sexuality education in schools. However, in the USA, a new set of pre-service teacher preparation standards has been developed for sexuality education and health. Australia has a set of generic teacher professional standards, but none specifically designed for teachers of relationships and sexuality education. This study aims to explore the possible development of such specific education professional standards for Australian teachers, by comparing and contrasting the knowledge, skills, and competencies exemplified in the prospective USA preparation standards with those in existing generic Australian teacher standards at graduate level. The analysis points to common areas of suitability, competencies, and effectiveness that could help pre-service/initial teachers, in-service teachers, and teacher educators find appropriate and relevant benchmarks for the teaching of timely and comprehensive relationships and sexuality education. The findings show structural similarities, content consistencies, and helpful commonalities in both standards’ sets, comprising seven USA teacher preparation standards, and seven Australian teacher professional standards. Such information may be useful for teachers and educators wishing to generate professional standards for the teaching of relationships and sexuality education in Australia.