Streptococcal Toxic Shock Syndrome

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Author(s)
Pandey, Manisha
Good, Michael
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Date
2019
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Australia

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Abstract

This invention relates to prevention and treatment of diseases caused by group A streptococci. More particularly, this invention relates to an antibodies or antibody fragments for treating or preventing group A streptococcus-associated toxic shock syndrome.

Provided herein are methods of immunizing against, treating or preventing streptococcal toxic shock syndrome in a subject, by administration of a group Astreptococcus M protein, inclusive of fragments, variants or derivatives thereof, or an antibody that binds, or is raised against the M protein and optionally a group A streptococcus superantigen protein, inclusive of fragments, variants or derivatives thereof, or an antibody or antibody fragment that binds, or is raised against, the superantigen protein.

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20210292398

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Awarded 2019-05-16

First IPC Mark: A61K39/09 (2006.01)

PCT/AU2019/050469

WO2019/218022 A1

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Subject

Clinical sciences

Immunology

Bacteriology

streptococcus

toxic shock syndrome

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Citation

Pandey, M; Good, M, Streptococcal Toxic Shock Syndrome, 2019

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