Streptococcal Toxic Shock Syndrome
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Good, Michael
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Australia
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Abstract
This invention relates to prevention and treatment of diseases caused by group A streptococci. More particularly, this invention relates to an antibodies or antibody fragments for treating or preventing group A streptococcus-associated toxic shock syndrome.
Provided herein are methods of immunizing against, treating or preventing streptococcal toxic shock syndrome in a subject, by administration of a group Astreptococcus M protein, inclusive of fragments, variants or derivatives thereof, or an antibody that binds, or is raised against the M protein and optionally a group A streptococcus superantigen protein, inclusive of fragments, variants or derivatives thereof, or an antibody or antibody fragment that binds, or is raised against, the superantigen protein.
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20210292398
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Awarded 2019-05-16
First IPC Mark: A61K39/09 (2006.01)
PCT/AU2019/050469
WO2019/218022 A1
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Subject
Clinical sciences
Immunology
Bacteriology
streptococcus
toxic shock syndrome
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Citation
Pandey, M; Good, M, Streptococcal Toxic Shock Syndrome, 2019