Although research suggests that bullied adolescents may respond to victimization with substance use, much of this prior work has been cross-sectional. Using longitudinal data from a community-based sample, we examine the impact of early bullying victimization on the initiation of substance use in adolescence after considering the potential influence of selection effects using propensity score matching. After matching, there were moderate differences between victims of bullying and control students for cigarette smoking and alcohol use, which was limited to those exposed to higher levels of bullying. Being bullied in childhood appears to have only minor effects on the onset of adolescent substance use in this sample.