Isolation of Xestosterol Esters of Brominated Acetylenic Fatty Acids from the Marine Sponge Xestospongia testudinaria
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Pham, NB
Butler, MS
Hooper, JNA
Moni, RW
Quinn, RJ
Butler, MS
Hooper, JNA
Moni, RW
Quinn, RJ
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1999
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Abstract
The CH2Cl2 extract of the marine sponge Xestospongia testudinaria inhibited [3H]DPCPX binding to rat-brain adenosine A1 receptors. Bioassay-guided fractionation led to the isolation of a known brominated acetylenic fatty acid 1 as the active component. Also isolated were two novel sterol esters 2 and 3. All structures were determined on the basis of their spectroscopic data.
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Journal of Natural Products
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62
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10
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Chemical sciences
Biological sciences
Biomedical and clinical sciences