Radical Carboxyarylation Approach to Lignans. Total Synthesis of (−)-Arctigenin, (−)-Matairesinol, and Related Natural Products
No Thumbnail Available
File version
Author(s)
Fischer, Joshua
J. Reynolds, Aaron
A. Sharp, Lisa
S. Sherburn, Michael
J. Reynolds, Aaron
A. Sharp, Lisa
S. Sherburn, Michael
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Amos B Smith, Carol Carr
Date
2004
Size
File type(s)
Location
License
Abstract
Total syntheses of seven biologically important lignan natural products, including (-)-arctigenin, (-)-matairesinol, and (-)-a-conidendrin, by way of a highly stereoselective domino radical sequence is presented. The reported stereochemistry of the natural product 7-hydroxyarctigenin is shown to be erroneous; a diastereoisomeric structure is assigned to the natural product.
Journal Title
Organic Letters
Conference Title
Book Title
Edition
Volume
6
Issue
9
Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status
Note
Access the data
Related item(s)
Subject
Chemical Sciences