Dielectrophoresis enrichment with built-in capacitive sensor microfluidic platform for tumor rare cell detection
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Bui, TT
Quoc, TV
Thanh, LP
Thuy, HTT
Dau, VT
Jen, CP
Duc, TC
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Kaohsiung, TAIWAN
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Abstract
This paper presents a dielectrophoresis (DEP) enrichment microfluidic platform with built-in anti-bodybased capacitive sensor for tumor rare cells detection. We take the advantages of the effective DEP actuation, the high selectivity property of antibody for rare cell immobilization, and the high sensitivity of differential capacitive sensing for quantitatively reading out, to produce advanced platform, toward single tumor cell detection for the rapid laboratory tests of cancers diagnoses and other metabolic diseases applications.
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TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems
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Biomedical engineering
Science & Technology
Engineering, Electrical & Electronic
Engineering
Differential capacitive sensing
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Quang, LD; Bui, TT; Quoc, TV; Thanh, LP; Thuy, HTT; Dau, VT; Jen, CP; Duc, TC, Dielectrophoresis enrichment with built-in capacitive sensor microfluidic platform for tumor rare cell detection, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, 2017, pp. 484-487