Dear Editor, A 53‐year‐old man was transferred by ambulance to our centre with retrosternal chest pain immediately after treatment for anaphylaxis. The patient initially sought care after experiencing shortness of breath, diaphoresis, nausea and dizziness following ingestion of amoxicillin/clavulanic acid. On arrival paramedics found the patient collapsed on his premises with cyanosed lips and generalised urticaria. The patient was treated with two injections of 0.5 mg adrenaline intramuscularly, and additionally given 700 mL i.v. isotonic fluid and 200 mg hydrocortisone intravenously. Approximately 2 min after the second dose of i.m. adrenaline and resolution of anaphylaxis symptoms, the patient began to experience central chest pain. ECG performed on route to our centre displayed sinus tachycardia and ST‐elevation in leads II, III and aVF. Aspirin, fentanyl, heparin and ticagrelor were administered and the cardiac catheter laboratory was activated pre‐hospitally. On arrival in the ED, the patient had minimal pain and vitals were BP 140/70 mmHg, heart rate 140/min and respiratory rate 20/min; peripheries were warm and well perfused. A subsequent ECG showed AF with presence of ST changes. The patient was transferred to the cardiac catheter laboratory where coronary angiogram revealed 50% stenosis of the LAD, minor disease of the circumflex, 60% stenosis mid‐right coronary artery and 99% stenosis distal right coronary artery (Fig. 1). Drug eluting stents were placed in the right coronary artery (Fig. 2), and the patient had an uneventful recovery.