Letter to the Editor and Author Response for "A systematic review and meta-analysis of randomized trials evaluating the efficacy of autologous skin cell suspensions for re-epithelialization of acute partial thickness burn injuries and split-thickness skin graft donor sites" by Bairagi, et al
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Griffin, Bronwyn
Banani, Tara
McPhail, Steven M
Kimble, Roy
Tyack, Zephanie
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Abstract
Dear Editor, We thank Holmes et al. for their interest in our systematic review and meta-analysis [1] and would like to submit the following response for their consideration:
- Randomized trials eligible for evaluation in this study were limited to partial thickness burn injuries managed with an autologous skin cell suspension which was a pre-specified inclusion criteria for our systematic review, published on the PROSPERO International Prospective Register of Systematic Reviews prior to commencing screening of database results (PROSPERO Record ID = CRD42019133171) [2]. As such, findings from a study conducted in full-thickness burn wounds although significant [3], were excluded from evaluation as they were beyond the scope of our systematic review and meta-analysis. The role of autologous skin cell suspensions (ASCS) in the management of full thickness burn wounds, could be better understood in a future review examining full thickness wounds. The findings from the study conducted in full thickness burn wounds that was referred to by the authors of the letter to the editor could be included in such a review [3].
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Burns
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Clinical sciences
Autologous skin cell suspension
Donor Site
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Meta-analysis
RECELL
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Bairagi, A; Griffin, B; Banani, T; McPhail, SM; Kimble, R; Tyack, Z, Letter to the Editor and Author Response for "A systematic review and meta-analysis of randomized trials evaluating the efficacy of autologous skin cell suspensions for re-epithelialization of acute partial thickness burn injuries and split-thickness skin graft donor sites" by Bairagi, et al, Burns, 2021