The Outcomes and Treatment Burden of Childhood Acute Myeloid Leukaemia In Australia, 1997-2008: A Report From The Australian Paediatric Cancer Registry

No Thumbnail Available
File version
Author(s)
Foresto, Steven A
Youlden, Danny R
Baade, Peter D
Hallahan, Andrew R
Aitken, Joanne F
Moore, Andrew S
Primary Supervisor
Other Supervisors
Editor(s)
Date
2015
Size
File type(s)
Location
License
Abstract

Childhood acute myeloid leukaemia (AML) requires intensive therapy and is associated with survival rates that are substantially inferior to many other childhood malignancies. We undertook a retrospective analysis of Australian Paediatric Cancer Registry data from 1997 to 2008 together with a single‐centre audit during the same period assessing burden on service delivery at a tertiary children's hospital (Royal Children's Hospital, Brisbane). Although survival improved from 54.3% (1997–2002) to 69.2% (2003–2008), childhood AML caused a disproportionate number of childhood cancer deaths, accounting for 5.5% of all childhood cancer diagnoses yet 7.9% of all childhood cancer mortality. Furthermore, treatment was associated with significant toxicity requiring intensive use of local health resources. Novel therapeutic strategies aimed at improving survival and reducing toxicity are urgently required.

Journal Title

Pediatric Blood & Cancer

Conference Title
Book Title
Edition
Volume

62

Issue

9

Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status
Note
Access the data
Related item(s)
Subject

Clinical sciences

Oncology and carcinogenesis

Oncology and carcinogenesis not elsewhere classified

Persistent link to this record
Citation
Collections