Human evolution: A tale from ancient genomes
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Willerslev, Eske
Orlando, Ludovic
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Abstract
The field of human ancient DNA (aDNA) has moved from mitochondrial sequencing that suffered from contamination and provided limited biological insights, to become a fully genomic discipline that is changing our conception of human history. Recent successes include the sequencing of extinct hominins, and true population genomic studies of Bronze Age populations. Among the emerging areas of aDNA research, the analysis of past epigenomes is set to provide more new insights into human adaptation and disease susceptibility through time. Starting as a mere curiosity, ancient human genetics has become a major player in the understanding of our evolutionary history.
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Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences
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372
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1713
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Evolutionary Biology not elsewhere classified
Biological Sciences
Medical and Health Sciences