This brief editorial describes an emerging area of machine learning technology called large language models (LLMs). LLMs, such as ChatGPT, are the technological disruptor of this decade. They are going to be integrated into search engines (Bing and Google) and into Microsoft products in the coming months. They will therefore fundamentally change the way patients and clinicians access and receive information. It is essential that telehealth clinicians are aware of LLMs and appreciate their capabilities and limitations.