Learning about biopsychosocial contributions to a sensitised pain system is a key target of many pain management programs for both adults and young people. The ‘Protectometer’ is a tool used to explore potential contributors, known as ‘danger in me’ (DIM) and ‘safety in me’ (SIM) cues. However, little is known about what topics are generated using the ‘Protectometer’, and to what extent these topics differ between young people and adults. A mixed-methods study was conducted to understand more about the types of danger and safety cues identified during pain management programs. Written ‘danger in me’ (n=504) and ‘safety in me’ (n=711) cues were collected from 96 participants (77 adults and 19 young people) who completed pain management programs across 15 groups at an adult or a young person pain centre. Reflexive thematic analysis identified four overarching themes: (1) Engaging with the environment, (2) In my body, (3) My emotional health, and (4) Activities and behaviours, with separate sub-themes for danger and safety cues. Codebook analysis of data into biological, psychological, or social domains was also performed. Integrating the results and comparing between age groups revealed differences between adults and young people for the most common types of danger cues, however safety cues were similar. Interestingly, the most common types of safety cues for both age groups were in the social domain. These findings highlight important areas to target in pain management education and treatment. They may help inform clinicians on key topics to address for each age group, and support the need to tailor interventions to age-specific clinical features. It also highlights the particular perceived relevance of social-based activities and environments in pain management therapies.