Controllable high-performance liquid marble micromixer

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Author(s)
Nguyen, Nhat-Khuong
Singha, Pradip
Dai, Yuchen
Sreejith, Kamalalayam Rajan
Tran, Du Tuan
Phan, Hoang-Phuong
Nguyen, Nam-Trung
Ooi, Chin Hong
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2022
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Abstract

A liquid marble is a liquid droplet coated with a shell of microparticles. Liquid marbles have served as a unique microreactor for chemical reactions and cell culture. Mixing is an essential task for liquid marbles as a microreactor. However, the potential of liquid marble-based microreactors is significantly limited due to the lack of effective mixing strategies. Most mixing strategies used manual and contact-based actuation schemes. This paper reports the development of a manipulation scheme that induces fluid motion into a liquid marble, leading to enhanced mixing. By inducing rotation on a horizontal axis, we significantly increased the mixing rate by 27.6 times compared to a non-actuated liquid marble and reduced the reaction time by more than 10 times. The proposed method provides a simple, continuous, precise, and controllable high-performance mixing strategy on a liquid marble platform.

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Lab on a Chip

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8

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DP170100277

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Chemical sciences

Engineering

Science & Technology

Life Sciences & Biomedicine

Physical Sciences

Technology

Biochemical Research Methods

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Nguyen, N-K; Singha, P; Dai, Y; Sreejith, KR; Tran, DT; Phan, H-P; Nguyen, N-T; Ooi, CH, Controllable high-performance liquid marble micromixer, Lab on a Chip, 2022, (8), pp. 1508-1518

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