Clinical decision-making in the management of whiplash associated disorders
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Sterling, Michele
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Ritchie, Carolyn
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Abstract
This thesis investigates various aspects of clinical decisionOmaking in the management
of individuals with acute whiplash associated disorders (WAD), with a primary focus on
physiotherapy professionals and one available clinical prediction rule designed for the
purpose of guiding prognostic judgments (the Whiplash CPR). WAD is a prevalent and
frequently chronic condition that is associated with substantial personal and societal
cost. It is currently challenging for healthcare practitioners to manage, as
heterogeneity in the population and nil to small effect sizes from clinical trials mean
that deciding on the best course of action may be difficult. Early and accurate
identification of prognostic risk has the potential to lessen current rates of progression
to chronic WAD, by enabling the provision of stratified care to more homogeneous
groups of individuals.
This body of work comprises a series of four studies using mixed methods. Study 1
comprised a systematic review of clinical prediction rules that relate to prognostic and
treatment decisionOmaking for the conservative management of neck pain. The study
was necessary in identifying available tools, and appraising stage of development,
quality and readiness for application, with the ultimate purpose of assisting healthcare
practitioners in the evaluation and selection of an appropriate tool for use in clinical
practice. Two independent reviewers assessed the eligibility, risk of bias,
methodological quality and stage of development of studies identified from a
systematic search of six databases. The results indicated that three out of nine
identified prognostic clinical prediction rules specific to acute WAD are at a stage of
development that lends support to clinical use. Use of the Whiplash CPR selected as
the focus of this thesis, was supported by maintenance of accuracy on validation, and
the satisfaction of most methodological quality criteria used in the review.
Study 2 focused on the Whiplash CPR and sought to assess its potential clinical utility.
A pragmatic crossOsectional design was used to investigate the level of agreement between physiotherapist estimatedO and Whiplash CPR classifiedO prognostic risk for
adults who presented to a participating physiotherapist (n=24) with acute WAD IOIII
(n=38). Agreement was found to be very low (29%, K= O0.03; 95%CI O0.17 to 0.12), and
physiotherapists likely underOidentified individuals at high risk of poor recovery (3%,
n=1/38). The findings of this study indicate that physiotherapists may benefit from
incorporating the Whiplash CPR into usual assessment and decisionOmaking processes
when attempting to gauge patient prognosis.
The presence of a validated, accurate and clinically useful clinical prediction rule, such
as the Whiplash CPR, has not historically ensured widespread use. Study 3 sought to
inform implementation of the Whiplash CPR through qualitative exploration of
healthcare practitioners’ (n=28) awareness and practice behaviours regarding clinical
prediction rules, and perceptions for using the Whiplash CPR in future practice. Six
focus group discussions were conducted, audioOrecorded, transcribed verbatim and
analysed using an inductive thematic approach. Many clinicians considered the
Whiplash CPR to be acceptable to them. Implementation themes including the
provision of an external driver of adoption, flexibility in how the Whiplash CPR could
be accessed and administered, and guidance regarding communication of its output to
patients, were identified as useful in promoting future use.
Finally, Study 4 related to management designed to specifically target individuals
identified by the Whiplash CPR as being at heightened risk of poor recovery. A
qualitative investigation was performed of physiotherapists’ (n=11) experiences of
delivering a novel psychological intervention (Stress Inoculation Training) to this
population as part of a randomised controlled trial. SemiOstructured interviews were
conducted, audioOrecorded, transcribed verbatim, and analysed thematically using a
withinO and acrossOcase strategy. Physiotherapists were found to support adding Stress
Inoculation Training to usual guidelineObased management. The feasibility and use of
the intervention in routine clinical practice were facilitated by confidence in the ability
to deliver the program, viewing it as falling within current scope of practice, and the
ability to selectively deliver the content to meet the needs of individual patients.
The findings of this body of work provide support to existing preliminary evidence that
physiotherapists may experience difficulty differentiating individuals who may and
may not recover from acute WAD. While progress has been made towards the rigorous
development of predictive tools to assist clinicians in this capacity, further validation
and impact analyses of existing models are ultimately required. At present, the
Whiplash CPR appears to be the most robust tool available for use in clinical practice. It
is therefore recommended that clinicians commence incorporating the CPR into
existing prognostic assessment and decisionOmaking processes. Physiotherapists
appear receptive to the using the Whiplash CPR and delivering new management
strategies that target individuals who are at heightened risk of developing chronic
WAD. However, education and support are needed to facilitate widespread changes to practice.
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Thesis (PhD Doctorate)
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Doctor of Philosophy (PhD)
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School Allied Health Sciences
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The author owns the copyright in this thesis, unless stated otherwise.
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Subject
Physiotherapy professionals
Neck pain
Stress Inoculation Training
Whiplash associated disorders
Whiplash CPR