Liquid marbles as chemical microreactors

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Ooi, Chin Hong

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Nguyen, Nam-Trung

Phan, Hoang Phuong

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2022-11-07
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Abstract

The miniaturisation of chemical and biological systems has become a research focus since the last century. Compared to conventional bulk reactors, microreactors have numerous advantages such as larger surface-area-to-volume ratio, higher heat and mass transfer rates as well as the reduction in energy demand and waste generation. Miniaturisation also improves control over reaction parameters and enhances reaction safety especially if hazardous substances are involved. The need for miniaturised reaction systems has led to the development of various microreactor platforms such as droplet-based microreactors. However, these platforms possess inherent drawbacks such as rapid evaporation and difficulty in handling a minute amount of liquid that have limited their implementation in practical applications. Liquid marbles are droplets covered with hydrophobic particles and present a platform that can potentially overcome the weaknesses of bare droplets. The coating layers completely isolate the interior liquids from the surrounding environment, thus conveniently encapsulating the reactions. Great efforts have been made over the past decade to demonstrate the feasibility of liquid marble-based microreactors for chemical and biological applications. Nevertheless, the inability to monitor reactions and the lack of an effective mixing method remains the main obstacles that can significantly hinder the potential of liquid marble-based microreactors. In order to benefit from the full potential of liquid marbles as universal microreactors, it is necessary to develop effective methods to enhance the mixing and monitoring abilities in liquid marbles. My Ph.D research focuses on developing methods to enhance the ability to monitor reaction and to improve mixing process in liquid marble-based platform.

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Thesis (PhD Doctorate)

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Doctor of Philosophy (PhD)

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School of Eng & Built Env

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The author owns the copyright in this thesis, unless stated otherwise.

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Subject

miniaturised reaction systems

microreactors

liquid marbles

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